Agent Name | Phosphorus trichloride |
---|---|
CAS Number | 7719-12-2 |
Formula | Cl3-P |
Major Category | Toxic Gases & Vapors |
Synonyms | Fosforo(tricloruro di) [Italian]; Fosfortrichloride [Dutch]; Phosphine, trichloro-; Phosphore(trichlorure de) [French]; Phosphorous chloride; Phosphorous trichloride; Phosphortrichlorid [German]; Phosphorus chloride (Cl6P2); Phosphorus chloride (PCl3); Trichlorophosphine; Trojchlorek fosforu [Polish; [ChemIDplus] UN1809 |
Category | Other Toxic Gases & Vapors |
Description | Colorless to yellow, fuming liquid with an odor like hydrochloric acid; [NIOSH] |
Sources/Uses | Used to produce pesticides, gasoline additives, plasticizers, dyes, and textile-finishing agents; also used as a chlorine donor and catalyst in chemical reactions; [ACGIH] |
Comments | Liquid causes second or third degree burns after short contact; [CHRIS] Highly corrosive to skin; [Quick CPC] Rats develop nephrosis and pulmonary edema after 4 hour exposures in the range of 100 ppm; 23 workers exposed to 1.8 to 27 ppm complained of eye and throat irritation; mild bronchitis was common and irritant asthma developed in some of the workers; [ACGIH] Toxic to the liver in a chronic study of animals; [Desai, H. Phosphorus and Phosphorus Compounds. In: Sullivan J, Krieger G (eds).Hazardous Materials Toxicology.Baltimore:Williams & Wilkins,1992;939] A corrosive substance that can cause pulmonary edema; [ICSC] A lachrymator; [CHEMINFO] |
Exposure Assessment | |
Skin Designation (ACGIH) | Insufficient data |
TIH | Yes |
Dangerous When Wet | Yes - A material that, by contact with water, is liable to become spontaneously flammable or to give off flammable or toxic gas at a rate greater than 1 L per kilogram of the material, per hour; [ERG 2004] |
TLV (ACGIH) | 0.2 ppm |
STEL (ACGIH) | 0.5 ppm |
PEL (OSHA) | 0.5 ppm |
MAK | 0.1 ppm |
IDLH (NIOSH) | 25 ppm |
Excerpts from Documentation for IDLHs | Other animal data: Cats and guinea pigs exposed for 6 hours at 0.7 ppm showed only mild signs of intoxication and a 1hour exposure at 2 to 4 ppm failed to produce severe signs of poisoning; however, a single 1hour exposure at 50 to 90 ppm resulted in serious disturbances [Butjagin 1904]. . . . Human data: Workers exposed to concentrations ranging from 1.8 to 27 ppm had symptoms that included burning of the eyes and throat, irritation of the pharyngeal mucous membranes, and mild bronchitis within 2 to 6 hours after exposure [Sassi 1952]. |
Vapor Pressure | 100 mm Hg |
Lethal Concentration | LC50 (rat) = 104 ppm/4 hr |
Adverse Effects | |
Lacrimator | Yes |
Toxic Pneumonitis | Yes |
Hepatotoxin | Hepatotoxin, Secondary |
Nephrotoxin | Yes |
Dermatotoxin | Skin Burns |
Links to Other NLM Databases | |
Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
Toxicity Information | |
Chemical Information | |
Related Information in HazMap | |
Diseases | Occupational diseases associated with exposure to this agent: |
Processes | Industrial Processes with risk of exposure: |