Agent Name

Methanearsonic acid

Alternative Name

Methylarsonic acid

CAS Number

124-58-3

Formula

C-H5-As-O3

Major Category

Metals

Synonyms

Arsonic acid, methyl-; DSMA (JMAF); Kyselina methylarsonova [Czech]; Methylarsonic acid [ISO]; Monomethylarsonate; Monomethylarsonic acid; [ChemIDplus] UN1557

Category

Arsenic Compounds, Organic

Description

White hygroscopic solid; [ICSC]

Sources/Uses

Used as herbicide in the past; [Merck Index] Not currently registered with the EPA for use in the US; [HSDB]

Comments

Oral LD50 (rat) = 961 mg/kg; [Sax] A mild skin, eye, and respiratory tract irritant; May cause kidney and liver injury; [ICSC] After ingestion of arsenic-rich wine, the majority of the arsenic was excreted in the urine in methylated form (methylarsonic acid & dimethylarsinic acid); Methylarsonic acid (MAA) fed to dairy cows in cottonseed ration had no apparent adverse effects; MAA was poorly absorbed and rapidly excreted in the urine; [HSDB] Arsenic is a known teratogen, but the effects of organic arsenicals is less clear. MAA is not likely to be a reproductive hazard at levels currently found in the environment; [REPROTOX] An irritant; [MSDSonline]

Exposure Assessment
PEL (OSHA)

0.5 mg/m3, as As

Vapor Pressure

0.00162 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Arsenic compound, solid, n.o.s."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

IARC Carcinogen

Possible Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: