Agent Name

Methylazoxymethanol

CAS Number

590-96-5

Formula

C2-H6-N2-O2

Major Category

Biological Agents

Synonyms

1-Hydroxymethyl-2-methyldiimide-2-oxide; MAM; Methanol, (methyl-ONN-azoxy)-; [ChemIDplus]

Category

Plant Toxins

Sources/Uses

The biologically active aglycone of cycasin (toxic substance found in seeds of various Cycas plants); [HSDB]

Comments

Acts as biological methylating agent; Similar in action to carcinogenic N-nitroso compounds; Nervous system malformations, mental defects, and tumors seen in offspring of rats and hamsters injected during pregnancy; Evidence for carcinogenicity in experimental animals; [HSDB] A neuroteratogen; [ChemIDplus] Causes changes in recordings from specific areas of brain in intraperitoneal toxic-dose studies of rats; [RTECS]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Reproductive Toxin

Yes

IARC Carcinogen

Possible Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.