Agent Name

Propargyl alcohol

CAS Number

107-19-7

Formula

C3-H4-O

Major Category

Other Classes

Synonyms

1-Propyn-3-ol; 2-Propyn-1-ol; 2-Propynyl alcohol; [NIOSH]

Category

Alcohols and Polyols, Other

Description

Colorless to straw-colored liquid with a mild, geranium odor; [NIOSH]

Sources/Uses

Used in steel and chemical production; Also used as a solvent stabilizer, fumigant, and corrosion inhibitor; [ACGIH]

Comments

Liquid causes second degree burns after contact for a few minutes. [CHRIS] Toxic to liver and kidneys in rats after repeated exposure to concentrations of 80 ppm; TLV Basis: Eye irritation and liver & kidney damage; [ACGIH] A lachrymator; [CHEMINFO]

Exposure Assessment
Skin Designation (ACGIH)

Yes

TLV (ACGIH)

1 ppm

MAK

2 ppm

Vapor Pressure

12 mm Hg

Odor Threshold Low

0.15 ppm

Lethal Concentration

LC50 (rat) = 1040 ppm/1 hr;

Explanatory Notes

Odor threshold from CHEMINFO; Flash point = 97 deg F; [CHEMINFO]

Adverse Effects
Lacrimator

Yes

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: