Agent Name

Methyl fluorosulfonate

CAS Number

421-20-5

Formula

C-H3-F-O3-S

Major Category

Other Classes

Synonyms

Fluorosulfuric acid, methyl ester; Magic Methyl; Methyl fluorosulfate; Methyl fluosulfonate; [ChemIDplus] UN1992

Category

Other Organic Compounds

Description

Colorless liquid with an ethereal odor; [Hawley] Cloudy colorless or yellow liquid; [MSDSonline]

Sources/Uses

Used as methylating agent in organic synthesis; [Merck Index]

Comments

Extremely toxic; May cause pulmonary edema; [Merck Index] Reacts with moisture producing corrosive vapor; A strong tissue irritant; [Hawley] Evolves hydrofluoric and sulfuric acid on contact with water; [ChemIDplus] Corrosive to skin of rabbits; May cause pulmonary edema and corneal damage; Emergency treatment: see "Hydrogen fluoride." [HSDB] A mutagen; Causes lacrimation and dyspnea in lethal-dose inhalation studies of rats; [RTECS] An irritant; May cause serious eye injury; May cause pulmonary edema; [MSDSonline]

Exposure Assessment
Lethal Concentration

LC50 (rat) = 5 ppm/1h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Flammable liquid, toxic, n.o.s."

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.