Agent Name

n-Propyl alcohol

Alternative Name

n-Propanol

CAS Number

71-23-8

Formula

C3-H8-O

Major Category

Solvents

Synonyms

n-Propanol; 1-Hydroxypropane; 1-Propyl alcohol; Albacol; Alcohol, propyl; Alcool propilico [Italian]; Alcool propylique [French]; Ethyl carbinol; Ethylcarbinol; Optal; Osmosol Extra; Propanol; Propanol-1; Propanole [German]; Propanolen [Dutch]; Propanoli [Italian]; Propyl alcohol (natural); Propyl alcohol, normal; Propylic alcohol; Propylowy alkohol [Polish]; n-Propan-1-ol; n-Propanol; n-Propyl alcohol; n-Propyl alkohol [German]; [ChemIDplus] UN1274

Category

Alcohols (<C12)

Description

Colorless liquid with a mild, alcohol-like odor; [NIOSH]

Sources/Uses

Used as a solvent, antiseptic, and chemical intermediate; [ACGIH] Used as a solvent in inks, pesticides, and lacquers; [HSDB]

Comments

A mucous membrane irritant similar to isopropyl alcohol, n-propyl alcohol produces narcosis in animals inhaling high concentrations. It causes severe liver injury in chronic feeding studies of laboratory animals. [ACGIH] Irritating to the eyes; Inhalation of high concentrations can cause CNS depression; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

100 ppm

PEL (OSHA)

200 ppm

IDLH (NIOSH)

800 ppm

Excerpts from Documentation for IDLHs

Human data: Mild irritation of the eyes, nose, and throat have been reported at 400 ppm [Nelson et al. 1943]. It has been reported that 5,700 mg/kg is the lethal oral dose [Durwald and Degen 1956]. [Note: An oral dose of 5,700 mg/kg is equivalent to a 70kg worker being exposed to about 94,000 ppm for 30 minutes, assuming a breathing rate of 50 liters per minute and 100% absorption.]

Vapor Pressure

21 mm Hg

Odor Threshold Low

0.03 ppm

Odor Threshold High

41 ppm

Lethal Concentration

LCLo (rat) = 4,000 ppm/4H

Explanatory Notes

Detection odor threshold from AIHA (mean = 5.3 ppm); Flash point = 23 deg C;

Half Life

No reports found; [TDR, p. 1052]

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: