Agent Name

n-Propyl alcohol

Alternative Name

n-Propanol

CAS Number

71-23-8

Formula

C3-H8-O

Major Category

Solvents

Synonyms

n-Propanol; 1-Hydroxypropane; 1-Propyl alcohol; Albacol; Alcohol, propyl; Alcool propilico [Italian]; Alcool propylique [French]; Ethyl carbinol; Ethylcarbinol; Optal; Osmosol Extra; Propanol; Propanol-1; Propanole [German]; Propanolen [Dutch]; Propanoli [Italian]; Propyl alcohol (natural); Propyl alcohol, normal; Propylic alcohol; Propylowy alkohol [Polish]; n-Propan-1-ol; n-Propanol; n-Propyl alcohol; n-Propyl alkohol [German]; [ChemIDplus] UN1274

Category

Alcohols (<C12)

Description

Colorless liquid with a mild, alcohol-like odor; [NIOSH]

Sources/Uses

Used as a solvent, antiseptic, and chemical intermediate; [ACGIH] Used as a solvent in inks, pesticides, and lacquers; [HSDB]

Comments

A mucous membrane irritant similar to isopropyl alcohol, n-propyl alcohol produces narcosis in animals inhaling high concentrations. It causes severe liver injury in chronic feeding studies of laboratory animals. [ACGIH] Irritating to the eyes; Inhalation of high concentrations can cause CNS depression; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

100 ppm

PEL (OSHA)

200 ppm

IDLH (NIOSH)

800 ppm

Excerpts from Documentation for IDLHs

Human data: Mild irritation of the eyes, nose, and throat have been reported at 400 ppm [Nelson et al. 1943]. It has been reported that 5,700 mg/kg is the lethal oral dose [Durwald and Degen 1956]. [Note: An oral dose of 5,700 mg/kg is equivalent to a 70kg worker being exposed to about 94,000 ppm for 30 minutes, assuming a breathing rate of 50 liters per minute and 100% absorption.]

Vapor Pressure

21 mm Hg

Odor Threshold Low

0.03 ppm

Odor Threshold High

41 ppm

Lethal Concentration

LCLo (rat) = 4,000 ppm/4H

Explanatory Notes

Detection odor threshold from AIHA (mean = 5.3 ppm); Flash point = 23 deg C;

Half Life

No reports found; [TDR, p. 1052]

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: