Agent Name

Methyl magnesium bromide

CAS Number

75-16-1

Formula

C-H3-Br-Mg

Major Category

Metals

Synonyms

Bromomethylmagnesium; Magnesium, bromomethyl-; Magnesium, methyl-, bromide (ethyl ether solution); Methylmagnesium bromide; Methyl magnesium bromide, in ethyl ether; [ChemIDplus] UN1928

Category

Metals, Organic Compounds

Description

Diethyl ether solution: Cloudy colorless liquid; [CAMEO] In 1.4m toluene/tetrahydrofuran solution: Orange liquid; [MSDSonline]

Sources/Uses

Used as alkylating agent in organic synthesis and as a Grignard reagent; [HSDB]

Comments

May have violent reaction with water; [HSDB] A strong reducing agent that is highly flammable; Reacts with water evolving methane; May form unstable peroxides on contact with air; [CAMEO] "Apart from their instability in air and their caustic basic properties, organomagnesium compounds and the precipitated inorganic magnesium salts produced during their use display no pronounced toxicity or side effects of environmental concern." [Ullmann] Reacts violently with water; May form explosive peroxides; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis and pulmonary edema; Inhalation of high concentrations can cause CNS depression; [MSDSonline]

Exposure Assessment
Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Methyl magnesium bromide in Ethyl ether;

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.