Agent Name

Methylmagnesium chloride

CAS Number

676-58-4

Formula

C-H3-Cl-Mg

Major Category

Metals

Synonyms

Chloromethylmagnesium; Magnesium, chloromethyl-; [ChemIDplus] UN3053

Category

Metals, Organic Compounds

Description

In 3 M Tetrahydrofuran solution: Brown liquid with an odor of ether; [MSDSonline]

Sources/Uses

Used as alkylating agent in organic synthesis and as a Grignard reagent; Also used to make tetramethyllead, styrallyl alcohol, and pharmaceuticals; [HSDB]

Comments

A dangerous fire and explosion risk; [Hawley] "Apart from their instability in air and their caustic basic properties, organomagnesium compounds and the precipitated inorganic magnesium salts produced during their use display no pronounced toxicity or side effects of environmental concern." [Ullmann] Reacts violently with water producing highly flammable gases; May form explosive peroxides; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline]

Exposure Assessment
Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Magnesium alkyls."

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.