Agent Name

Methyl methanesulfonate

CAS Number

66-27-3

Formula

C2-H6-O3-S

Major Category

Other Classes

Synonyms

MMS; Methanesulfonic acid methyl ester; Methanesulphonic acid methyl ester; Methyl ester of methanesulfonic acid; Methyl ester of methanesulphonic acid; Methyl mesylate; Methyl methanesulfonic acid; Methyl methanesulphonate; Methyl methansulfonate; Methyl methansulphonate; Methylester kyseliny methansulfonove [Czech]; Methylmethane sulfonate; Methylmethanesulfonate; Methylmethanesulphonate; Methylmethansulfonat [German]; as-Dimethyl sulfite; as-Dimethyl sulphite; [ChemIDplus]

Category

Sulfur Compounds

Description

Colorless liquid; mp = 20 deg C; [HSDB] Colorless to amber liquid; [CAMEO] Clear faintly yellow liquid; [MSDSonline]

Sources/Uses

Used as experimental mutagen, teratogen, and brain carcinogen; [HSDB]

Comments

At a dose of 2.8-800 mg/kg body weight for up to 350 days, side effects in cancer patients included gastrointestinal and liver injury; [HSDB] Embryotoxic at 100 mg/kg in rats; No human data; [REPROTOX] May cause skin, eye, mucous membrane, and respiratory tract irritation; [CAMEO] An irritant; [MSDSonline]

Exposure Assessment
Vapor Pressure

0.31 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Reproductive Toxin

Yes

IARC Carcinogen

Probable Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Other Information

No other related information on this agent was found.