Agent Name

Myristicin

CAS Number

607-91-0

Formula

C11-H12-O3

Major Category

Biological Agents

Synonyms

1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)-; 4-Methoxy-6-(2-propenyl)-1,3-benzodioxole; 5-Allyl-1-methoxy-2,3-(methylenedioxy)benzene; 6-Allyl-4-methoxy-1,3-benzodioxole; Benzene, 5-allyl-1-methoxy-2,3-(methylenedioxy)-; [ChemIDplus]

Category

Plant Toxins

Description

Colorless liquid; [Merck Index]

Sources/Uses

An aromatic ether found in nutmeg, parsley, and carrots; [Merck Index] Thought to be the main active ingredient in nutmeg; [Goldfrank, p. 626]

Comments

Emergency treatment: "Plants- nutmeg"; [HSDB] Toxicity occurs after ingestion of 1-3 whole nuts or 1-2 tablespoons of ground nutmeg; CNS symptoms predominate and may resemble the anticholinergic syndrome with flushing, dryness, tachycardia, hypertension, and delirium with resolution usually within 24 hours; Higher doses cause coma, and one fatal case has been reported; [Goldfrank, p. 626] Effects in high-dose animal studies include general anesthesia and fatty liver degeneration; [RTECS] An irritant; Targets nerves; [Sigma MSDS]

Reference Link

INCHEM: Myristica fragrans Houtt. (PIM 355 - 1997)

Exposure Assessment
Vapor Pressure

0.00646 mm Hg

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Other Information

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