Agent Name

N,N,N',N'-Tetramethyl-1,2-ethanediamine

CAS Number

110-18-9

Formula

C6-H16-N2

Major Category

Nitrogen Compounds

Synonyms

1,2-Bis-(dimethylamino)ethane; 1,2-Ethanediamine, N,N,N',N'-tetramethyl-; Dimethyl(2-(dimethylamino)ethyl)amine; Ethylenediamine, N,N,N',N'-tetramethyl-; N,N,N',N'-Tetramethyl-1,2-diaminoethane; N,N,N',N'-Tetramethylethanediamine; N,N,N',N'-Tetramethylethylenediamine; Propamine D; TMEDA; TEMED; Tetrameen; Tetramethyl ethylene diamine; Tetramethyldiaminoethane; Tetramethylethylenediamine; 1,2-Di-(dimethylamino)ethane; [ChemIDplus] UN2372

Category

Amines, Aliphatic

Description

Colorless liquid with a mild odor of ammonia; [HSDB] Hygroscopic; [CHEMINFO]

Sources/Uses

Used to make epoxy curing agents, polyurethane, and quaternary ammonium compounds; Also used in textile finishing agents, as a corrosion inhibitor, acrylamide polymerization catalyst, and reagent; [HSDB] Used as polymerization accelerator in gel electrophoresis, a solvent, and an oxidizing reagent; [Merck Index]

Comments

Emergency treatment: Irritants; [HSDB] Corrosive to skin and eyes, based on animal studies; [CHEMINFO] Highly flammable; Can cause burns; [eChemPortal: ESIS] Necrosis observed 14 days following three minute exposure to rabbit skin; Severe eye irritant in rabbits; Lesions of the brain observed in oral lethal-dose study of rats; No evidence of mutagenicity; [EPA HPVIS] Causes burns; Toxic by ingestion; May be absorbed through skin; If inhaled may cause corrosive effects to upper respiratory tract and lungs; [Aldrich MSDS]

Exposure Assessment
Vapor Pressure

16.7 mm Hg

Odor Threshold Low

0.1 ppm

Lethal Concentration

LC50 (rat) = 1,318 ppm/4h

Explanatory Notes

Odor threshold (unspecified) from CHEMINFO;

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: