Agent Name

N-Isopropylacrylamide

CAS Number

2210-25-5

Formula

C6-H11-N-O

Major Category

Nitrogen Compounds

Synonyms

2-Propenamide, N-(1-methylethyl)-; Acrylamide, N-isopropyl-; Isopropyl acrylamide; Isopropylamid kyseliny akrylove [Czech]; N-(1-Methylethyl)-2-propenamide; Nipam; [ChemIDplus]

Category

Other Nitrogen Compounds

Description

Solid; [Hawley]

Sources/Uses

Used in binders for textiles, paper, adhesives, detergents, and cosmetics; [Hawley]

Comments

Crude solutions may cause skin irritation; Causes hind quarter paralysis and head tremors in cats administered intraperitoneally at total cumulative dose of 840 mg/kg over 18 day period (fully recovered after five weeks); Testicular atrophy (degeneration of epithelial cells of the seminiferous tubules) observed in mice following repeated oral doses; [HSDB] A moderate eye irritant; Causes spastic paralysis and hemorrhage in dermal lethal-dose study of rabbits and oral lethal-dose study or rats; Causes changes in testicular weight in eight week intermittent oral study of mice; [RTECS] An irritant; [Aldrich MSDS]

Exposure Assessment
Vapor Pressure

0.02 mm Hg

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: