Agent Name

N-Methyl-N'-nitro-N-nitrosoguanidine

CAS Number

70-25-7

Formula

C2-H5-N5-O3

Major Category

Nitrogen Compounds

Synonyms

1-Methyl-1-nitroso-3-nitroguanidine; 1-Methyl-3-nitro-1-nitrosoguanidine; 1-Nitroso-3-nitro-1-methylguanidine; Guanidine, 1-methyl-3-nitro-1-nitroso-; Guanidine, N-methyl-N'-nitro-N-nitroso-; MNG; MNNG; Methylnitronitrosoguanidine; N'-Nitro-N-nitroso-N-methylguanidine; N-Methyl-N'-nitro-N-nitrosoguanidine; N-Methyl-N-nitroso-N'-nitroguanidine; N-Methyl-N-nitrosonitroguanidin [German]; N-Methylo-N'-nitro-N-nitrozoguanidyny [Polish]; N-Metylo-N'-nitro-N-nitrozoguanidyny [Polish]; N-Nitroso-N'-nitro-N-methylguanidine; N-Nitroso-N-methyl-N'-nitroguanidine; N-Nitroso-N-methylnitroguanidine; [ChemIDplus] UN1325

Category

Other Nitrogen Compounds

Description

Yellow solid; [Merck Index] Pale yellow to pink solid; Light sensitive, changes color to orange and green; [HSDB] Yellow crystals; [Aldrich MSDS]

Sources/Uses

Used as experimental carcinogen and mutagen; Used formerly to make diazomethane; [Merck Index]

Comments

Mutagenic to human cells; No expected human exposure outside of laboratories where it is used for research; Evidence of carcinogenicity and mutagenicity in experimental animals; [HSDB] Highly flammable, explosive, and violently reactive with water; [CAMEO] A skin and eye irritant; [eChemPortal: ESIS] Toxic to embryonic development in experimental animals; ]REPROTOX] Causes convulsions, acute pulmonary edema, and ulceration or bleeding from stomach in oral lethal-dose studies of rats; Causes changes to liver, GI tract, blood, and lipids in oral toxic-dose studies of mice; [RTECS] An irritant; [Aldrich MSDS]

Exposure Assessment
Vapor Pressure

0.00012 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Flammable solid, organic, n.o.s."

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Reproductive Toxin

Yes

IARC Carcinogen

Probable Carcinogen

NTP Carcinogen

Anticipated Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.