Agent Name

N-Methylacetamide

CAS Number

79-16-3

Formula

C3-H7-N-O

Major Category

Nitrogen Compounds

Synonyms

Methyl acetamide; Acetamide, N-methyl-; Acetamide, methyl-; Acetic acid, amide, N-methyl; Methylacetamide; Monomethylacetamide; N-Methyl acetamide; N-Monomethylacetamide; X 44; [ChemIDplus]

Category

Other Nitrogen Compounds

Description

Solid; mp = 28 deg C; [HSDB] White crystalline solid; mp = 26-28 deg C; [Alfa Aesar MSDS]

Sources/Uses

Used as a solvent, in electrochemistry, and as a pesticide registered with the EPA; [HSDB]

Comments

Mice that died 24-48 hours following administration exhibited toxic hepatitis, necrosis of pancreas, and testicular atrophy; Causes hyperglycemia in rats; A diabetogen in experimental animals that produces an insulin-resistant state (rather than insulin deficiency); Teratogenic effects and embryotoxicity observed in rats and rabbits (dermal, gavage, and intraperitoneal routes); [HSDB] Causes changes in renal tubules, changes in bone marrow, and weight loss in 90-day constant feeding study of rats (90 gm/kg); [RTECS] An irritant; [Alfa Aesar MSDS]

Exposure Assessment
Vapor Pressure

0.44 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: