Agent Name

N(1)-Acetylphenylhydrazine

CAS Number

114-83-0

Formula

C8-H10-N2-O

Major Category

Nitrogen Compounds

Synonyms

1-Acetyl-2-phenylhydrazine; 1-Phenyl-2-acetylhydrazine; APH; Acetic acid phenylhydrazone; Acetylphenylhydrazine; Fenylhydrazid kyseliny octove [Czech]; Hydracetin; N'-Phenylacethydrazide; N-Acetyl-N'-phenylhydrazine; Pyrodin; Pyrodine; beta-Acetylphenylhydrazine; [ChemIDplus]

Category

Hydrazides

Description

Colorless or white solid; [CAMEO] Off-white powder; [MSDSonline]

Sources/Uses

Used as an intermediate for pharmaceuticals and other chemicals; Formerly used to treat polycythemia; [HSDB]

Comments

Emergency treatment: "Hydrazines"; Hydrazines can cause severe eye damage. They can cause seizures, liver injury, hemolysis, and delayed pulmonary edema. [HSDB] Oral LD50 (mouse) = 270 mg/kg; Causes methemoglobinemia in feeding studies of dogs; [RTECS] An irritant; [MSDSonline] See "Hydrazine."

Exposure Assessment
Vapor Pressure

7.3E-5 mm Hg

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Other Information

No other related information on this agent was found.