Agent Name

Nicarbazin

CAS Number

330-95-0

Formula

C13-H10-N4-O5.C6-H8-N2-O

Major Category

Other Uses

Synonyms

4,4'-Dinitrocarbanilide, compd. with 4,6-dimethyl-2-pyrimidinol; MK 75; MK 75 (VAN); N,N'-Bis(4-nitrophenyl)urea compd. with 4,6-dimethyl-2-pyrimidinol (1:1); Nicarb; Nicarbasin; Nicarbazine; Nicoxin; Nicrazin; Nicrazine; Nirazin; 1,3-Bis(4-nitrophenyl)urea-4,6-dimethylpyrimidin-2-ol; Carbanilide, 4,4'-dinitro-, compd. with 4,6-dimethyl-2-pyrimidinol (1:1); Urea, N,N'-bis(4-nitrophenyl)-, compd. with 4,6-dimethyl-2(1H)-pyrimidinone (1:1); [ChemIDplus]

Category

Animal Feed Additives

Description

Light yellow solid; [HSDB]

Sources/Uses

Used as a coccidiostat for poultry and to reduce egg hatching in resident Canadian geese; [HSDB]

Comments

An equimolar complex of 4,4'-dinitrocarbanilide and 2-hydroxy-4,6-dimethylprimidine; A moderate eye irritant; Oral LD50 (rat) >10,000 mg/kg; In high-dose feeding studies of dogs over 2 years, it caused liver injury in doses >240 mg/kg/day; In another animal study, the NOEL for maternal and fetal toxicity was 200 mg/kg/day; [HSDB] An irritant; [MSDSonline]

Reference Link

EPA Pesticide Chemical Search

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Processes

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