Agent Name

Nivalenol

CAS Number

23282-20-4

Formula

C15-H20-O7

Major Category

Biological Agents

Synonyms

12,13-Epoxy-3,4,7,15-tetrahydroxytrichothec-9-en-8-one; 3-alpha,4-beta,7-alpha,15-Tetrahydroxy-12,13-epoxytrichothec-9-en-8-one; 3-alpha,4-beta,7-alpha,15-Tetrahydroxyscirp-9-en-8-one; Trichothec-9-en-8-one, 12,13-epoxy-3,4,7,15-tetrahydroxy-, (3alpha,4beta,7alpha)-; Trichothec-9-en-8-one, 12,13-epoxy-3alpha,4beta,7alpha,15-tetrahydroxy-; [ChemIDplus]

Category

Mycotoxins

Description

Solid; [Merck Index]

Sources/Uses

Trichothecene mycotoxin found in Fusarium nivale; [Merck Index]

Comments

Trichothecene mycotoxins causes bone marrow suppression, leukopenia, immunosuppression, and secondary sepsis; [HSDB] May cause necrotic lesions to skin and mucosa; [Merck Index] A vesicant to skin, can cause irritation to severe tissue destruction; [MSDSonline] See "Deoxynivalenol."

Reference Link

PubMed Full-Text: Mycotoxins

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Other Information

No other related information on this agent was found.