Agent Name

N,N'-Di-sec-butyl-p-phenylenediamine

CAS Number

101-96-2

Formula

C14-H24-N2

Major Category

Nitrogen Compounds

Synonyms

1,4-Benzenediamine, N,N'-bis(1-methylpropyl)-; Antioxidant 22; Du Pont Gasoline Antioxidant No. 22; Kerobit BPD; N,N'-Di-s-butyl-p-phenylenediamine; N,N'-Di-sec-butyl-p-phenyldiamine; N,N'-Di-sec-butylparaphenylenediamine; N,N'-Di-sek.butyl-p-fenylendiamin [Czech]; Santoflex 44; Tenamene 2; Topanol M; UOP 5; p-Phenylenediamine, N,N'-di-sec-butyl-; [ChemIDplus] UN2922

Category

Amines, Aromatic

Description

Pale yellow or amber to red liquid; mp = 18 deg C; [HSDB] Dark red liquid; [MSDSonline]

Sources/Uses

Used in gasoline (gum inhibitor, antioxidant, and stabilizer) and styrene-butadiene rubbers (antioxidant and antiozonant); [HSDB]

Comments

Emergency treatment: "Paraphenylenediamine"; In sensitized individuals, paraphenylenediamine may cause allergic contact dermatitis following application as a hair dye and asthma following inhalation; Following ingestion, can cause angioneurotic edema, methemoglobinemia, acute tubular necrosis, and hepatotoxicity; An adult died after ingestion of 3 grams of p-phenylenediamine; Another adult who ingested 1800 mg developed angioneurotic edema and acute renal failure; [HSDB] A strong irritant that may cause burns; [CAMEO] Highly irritating or corrosive to skin and eyes, based on animal studies; [eChemPortal: HPVIS] Causes burns; May cause skin sensitization; Toxic if swallowed; Absorbed through skin; [Aldrich MSDS] See "p-Phenylenediamine."

Exposure Assessment
Vapor Pressure

0.00156 mm Hg

Lethal Concentration

LCLo (rat) = 600 mg/m3/6h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Corrosive liquid, toxic, n.o.s."

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: