Agent Name

N,N'-Diphenylguanidine

CAS Number

102-06-7

Formula

C13-H13-N3

Major Category

Plastics & Rubber

Synonyms

1,3-Difenylguanid [Czech]; 1,3-Diphenylguanidine; Accelerator D; DFG; DPG; DPG (VAN); DPG accelerator; Denax; Denax DPG; Diphenylguanidine; Dwufenyloguanidyna [Polish]; Guanidine, 1,3-diphenyl-; Guanidine, N,N'-diphenyl-; Melaniline; Nocceler D; Vulcafor DPG; Vulkacit D; Vulkacit D/C; Vulkacite D; Vulkazit; s-Diphenylguanidine; [ChemIDplus]

Category

Rubber Additives

Description

Colorless or white solid; [ICSC] White powder; [MSDSonline]

Sources/Uses

Used as a vulcanization accelerator, an activator for other rubber accelerators, and a primary material for standardizing acids; [HSDB] Formerly was contained in "Carbamix" used to patch test for allergic contact dermatitis; Workers may be exposed to rubber items in homemaking and in the metal, health, laboratory, and building industries; [Kanerva, p. 1789]

Comments

A mild eye irritant; May affect human reproduction, based on animal studies; [ICSC] Based on animal studies, a mild eye irritant, but not a skin irritant; Metabolized quickly and eliminated in urine and feces; Has effects on liver and nervous system in feeding studies; Not genotoxic; Not teratogenic; Fetotoxic at maternotoxic doses; [Reference #2]

Reference Link

Occupational allergic contact dermatitis from diph... [Contact Dermatitis. 1994] - PubMed result

Exposure Assessment
Vapor Pressure

8.45E-6 mm Hg

Reference Link

OECD SIDS: 1,3-Diphenylguanidine - 2002

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: