Agent Name

N,N-Dimethyl-p-benzenediamine

Alternative Name

Dimethyl-p-phenylenediamine

CAS Number

99-98-9

Formula

C8-H12-N2

Major Category

Nitrogen Compounds

Synonyms

Dimethyl-p-phenylenediamine; 1,4-Benzenediamine, N,N-dimethyl-; 4-(Dimethylamino)aniline; 4-(Dimethylamino)benzenamine; 4-(Dimethylamino)phenylamine; 4-Amino-N,N-dimethylaniline; C.I. 76075; CI 76075; DMPD; Dimethyl-4-phenylenediamine; Dimethyl-para-phenylenediamine; N,N-Dimethyl-1,4-benzenediamine; N,N-Dimethyl-1,4-phenylenediamine; N,N-Dimethyl-p-fenylendiamin [Czech]; N,N-Dimethyl-p-phenylenediamine; p-(Dimethylamino)aniline; p-Amino-N,N-dimethylaniline; p-Aminodimethylaniline; p-Dimethylaminophenylamine; p-Phenylenediamine, N,N-dimethyl-; [ChemIDplus]

Category

Amines, Aromatic

Description

Colorless to reddish-violet solid; [HSDB] Black or grey solid; [MSDSonline]

Sources/Uses

Used to make methylene blue, other dyes, diazonium chloride, and other compounds; Also used as a photodeveloper and reagent (i.e. detection of hydrogen sulfide and chloramine); [HSDB]

Comments

A skin and eye irritant; May cause skin sensitization; [CAMEO] A skin and eye irritant; Three cases of allergic contact dermatitis reported in bacteriology lab; Induces mild methemoglobinemia in rats; Can be absorbed through skin, with small amounts being highly toxic; [HSDB] Causes hemorrhage, irritation, and allergic dermatitis in dermal studies with humans; Causes convulsions and dyspnea in inhalation lethal-concentration studies with guinea pigs and rabbits; Caused convulsions in oral lethal-dose study of cats; [RTECS] An irritant; Toxic by inhalation or skin absorption; Fatal by ingestion; [Aldrich MSDS]

Exposure Assessment
Vapor Pressure

0.00791 mm Hg

Lethal Concentration

LCLo (rabbit) = 0.5 ppm

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Skin Sensitizer

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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