Agent Name

Clorophene

Alternative Name

o-Benzyl-p-chlorophenol

CAS Number

120-32-1

Formula

C13-H11-Cl-O

Major Category

Other Classes

Synonyms

o-Benzyl-p-chlorophenol; 2-Benzyl-4-chlorophenol; 4-Chloro-2-(phenylmethyl)phenol; 4-Chloro-2-benzylphenol; 4-Chloro-alpha-phenyl-o-cresol; 4-Chloro-alpha-phenyl-ortho-cresol; 5-Chloro-2-hydroxydiphenylmethane; Benzylchlorophenol; Bio-Clave; Chlorophene; Clorofeno [INN-Spanish]; Clorofenum [INN-Latin]; Clorophene; Ketolin-H; Neosabenyl; Orthobenzyl-p-chlorophenol; Orthobenzylparachlorophenol; Phenol, 4-chloro-2-(phenylmethyl)-; Santophen 1; Santophen 1 flake; Santophen 1 solution; Santophen I; Santophen I germicide; Septiphene; o-Benzylchlorophenol; o-Cresol, 4-chloro-alpha-phenyl-; p-Chloro-o-benzylphenol; [ChemIDplus] UN2020

Category

Halogenated Polyaromatics

Description

White to light tan or pink solid; [Hawley]

Sources/Uses

Used in household, hospital, and veterinary disinfectants; Also used as a fungicide, herbicide, antimicrobial, and cosmetics preservative; [HSDB] Used as a disinfectant (swimming pool decks, industrial water systems, poultry houses and other farming premises, food processing, and restaurants); [Reference #1]

Comments

Emergency medical treatment: see phenol and related agents; A skin irritant; One of the chemicals that can cause toxic vitiligo; [HSDB] Chemical leukoderma is indistinguishable from vitiligo; May occur in workers exposed to hydroquinones, catechols, phenols, or mercaptoamines; [White, p. 285] A mutagen, tumorigen, and mild skin irritant; Causes somnolence and convulsions in lethal-dose studies of mice; [RTECS] A skin, mucous membrane, and respiratory tract irritant; Corrosive to eyes; "It has also caused severe porphyria cutanea tarda." [CAMEO] Chemical associated with acquired porphyria include hexachlorobenzene, 2,4-dichlorophenol, 2,4,5-trichlorophenol, 2,3,7,8-tetrachlorodibenzo-p-dioxin, o-benzyl-p-chlorophenol, 2-benzyl-p-dichlorophenol, vinyl chloride, lead, and aluminum; However, recent studies have failed to find an association between 2,3,7,8-tetrachlorodibenzo-p-dioxin and porphyrin levels; [LaDou, p. 266, 519] Corrosive to eyes; Causes kidney injury in chronic animal experiments and is a possible human carcinogen; [Reference #1] An irritant; Effects in high-dose animal studies include convulsions; [MSDSonline]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
Vapor Pressure

5.06E-5 mm Hg

Lethal Concentration

LC (rat) > 13,200 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Chlorophenols, solid."

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: