Agent Name

Ochratoxin B

CAS Number

4825-86-9

Formula

C20-H19-N-O6

Major Category

Biological Agents

Synonyms

Alanine, N-((8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenyl-, (-)-; L-Phenylalanine, N-((3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl)-, (R )-; [ChemIDplus] UN3462

Category

Mycotoxins

Description

Solid with blue fluorescence; [Merck Index]

Sources/Uses

A toxic metabolite of Aspergillus ochraceus, Aspergillus sulphureus, Aspergillus melleus, and Penicillium viridicatum molds. Ochratoxins are natural contaminants of corn, peanuts, storage grains, cottonseed, and other decaying vegetables; Used as an experimental teratogen and carcinogen; [Merck Index]

Comments

Less toxic dechloro derivative of Ochratoxin A; [Merck Index] Ochratoxin B is about 1/10 as potent as Ochratoxin A and C; Ochratoxins are toxic to the kidneys in animal experiments and may cause Balkan endemic nephropathy in humans; [HSDB] An irritant; Targets the liver and kidneys; [MSDSonline] See "Ochratoxin A."

Reference Link

PubMed Full-Text: Mycotoxins

Exposure Assessment
Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxins, extracted from living sources, solid, n.o.s."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

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