Agent Name

Ochratoxin C

CAS Number

4865-85-4

Formula

C22-H22-Cl-N-O6

Major Category

Biological Agents

Synonyms

Alanine, N-((5-chloro-8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenyl-, ethyl ester, L-; L-Phenylalanine, N-((5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl)-, ethyl ester, (R)-; [ChemIDplus]

Category

Mycotoxins

Sources/Uses

A toxic metabolite of Aspergillus ochraceus, Aspergillus sulphureus, Aspergillus melleus, and Penicillium viridicatum molds. Ochratoxins are natural contaminants of corn, peanuts, storage grains, cottonseed, and other decaying vegetables; Used as an experimental teratogen and carcinogen; [Merck Index] Produced by Penicillium verrucosum, a common contaminant of barley; [Reference #1]

Comments

Ethyl ester of Ochratoxin A and equally toxic; [Merck Index] Ochratoxin B is about 1/10 as potent as Ochratoxin A and C; Ochratoxins are toxic to the kidneys in animal experiments and may cause Balkan endemic nephropathy in humans; [HSDB] See "Ochratoxin A."

Reference Link

PubMed Full-Text: Mycotoxins

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

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