Agent Name

Octamethylcyclotetrasiloxane

CAS Number

556-67-2

Formula

C8-H24-O4-Si4

Major Category

Metals

Synonyms

Cyclic dimethylsiloxane tetramer; Cyclotetrasiloxane, octamethyl-; KF 994; NUC silicone VS 7207; OMCTS; Oktamethylcyklotetrasiloxan [Czech]; SF 1173; Silicone SF 1173; UC 7207; Union carbide 7207; VS 7207; Cyclotetrasiloxane, 2,2,4,4,6,6,8,8-octamethyl-; [ChemIDplus]

Category

Metalloid Compounds (Silicon)

Description

Colorless liquid; mp = 17.5 deg C; [ICSC]

Sources/Uses

Used to make methyl silicon oils, silicone fluids, and elastomers; Also used in a variety of applications including fermentation processes, instant coffee production, paper coatings and sizing, diet soft drinks, waste yeast tanks, food washing solutions, adhesives, textiles, de-asphalting, boiler treatments, detergents, cleaning solutions, surfactants, cosmetic products, and polishes; [HSDB]

Comments

No listed effects of short-term or long-term exposure; Can be absorbed through skin; [ICSC] Volunteers were exposed to 10 ppm for 1 hour and then again 3 months later; No immunotoxic or inflammatory effects were detected; Silicones cause foreign body reactions when injected or implanted in tissues; [HSDB] An irritant; [MSDSonline]

Exposure Assessment
WEEL

10 ppm

Vapor Pressure

1.05 mm Hg

Lethal Concentration

LC50 (rat) = 36,000 mg/m3/4h

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Processes

Industrial Processes with risk of exposure: