Agent Name

Tetrachloronaphthalene

CAS Number

1335-88-2

Formula

C10-H4-Cl4

Major Category

Other Classes

Synonyms

Halowax; Nibren wax; Seekay wax; [NIOSH]

Category

Halowaxes

Description

Colorless to pale-yellow solid with an aromatic odor; [NIOSH]

Sources/Uses

"There are no known commercial uses for purified individual isomers of di-, tri-, tetra-, penta-, hexa-, or heptachloronaphthalene." [HSDB]

Comments

Chlorinated naphthalenes may be absorbed through the skin. They cause liver injury and hyperkeratosis in experimental animals. Penta- and hexachloronaphthalene may cause in exposed workers acne-like lesions that itch severely. Tri-, tetra-, and octachloronaphthalene are non-acnegenic under the conditions of industrial use. Nine occupational fatalities from chlorinated naphthalene poisoning have been reported. Most cases of intoxication among cable workers, assemblers, and laborers involve either penta- or hexachloronaphthalene. A nonfatal case of toxic hepatitis was reported in an 18 year old female who was soldering electrical condensers. [ACGIH] Acne-form dermatitis is listed as an adverse effect for all of the halowaxes except trichloronaphthalene in the NIOSH Pocket Guide. May cause liver injury; [ICSC]

Reference Link

CHLORINATED NAPHTHALENES (CICAD 34, 2001)

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

Bioaccumulates

Yes

TLV (ACGIH)

2 mg/m3

PEL (OSHA)

2 mg/m3

Excerpts from Documentation for IDLHs

Animal data: It has been stated that tetrachloronaphthalene has been shown to be less toxic to the liver than more highly chlorinated derivatives of naphthalene [ACGIH 1986]. . . . Basis for revised IDLH: Due to a lack of relevant acute toxicity data, the IDLH for tetrachloronaphthalene remains "Unknown."

Vapor Pressure

1.0E-6 mm Hg

Explanatory Notes

Flash point = 210 deg C;

Adverse Effects
Hepatotoxin

Hepatotoxin, Primary

Dermatotoxin

Chloracne

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: