Agent Name

Oxydemeton-methyl

CAS Number

301-12-2

Formula

C6-H15-O4-P-S2

Major Category

Pesticides

Synonyms

Aimco systox; Demeton-S methyl sulfoxide; Demeton-S-methyl sulfoxid [German]; Demeton-S-methyl sulfoxide; Demeton-S-methyl-sulfoxid [German]; Demeton-methyl sulphoxide; Dimethyl S-(2-eththionylethyl) thiophosphate; ENT 24,964; Ethanethiol, 2-(ethylsulfinyl)-, S-ester with O,O-dimethyl phosphorothioate; Isomethylsystox sulfoxide; Metaisosystox sulfoxide; Metaisosystoxsulfoxide; Metasystemox; Metasystemox R; Metasystox-R; Metasytox R; Methyl oxydemeton S; Metilmercaptofosoksid (USSR); O,O-Dimethyl S-(2-(ethylsufinyl)ethyl) thiophosphate; O,O-Dimethyl S-(2-(ethylsulfinyl)ethyl) monothiophosphate; O,O-Dimethyl S-(2-(ethylsulfinyl)ethyl) phosphorothioate; O,O-Dimethyl S-(2-eththionylethyl) phosphorothioate; O,O-Dimethyl S-(2-ethylsulfinyl)ethyl thiophosphate; O,O-Dimethyl S-ethylsulphinylethyl phosphorothiolate; O,O-Dimethyl-S-(2-aethylsulfinyl-aethyl)-thiolphosphat [German]; O,O-Dimethyl-S-(2-ethylsulfinyl-ethyl)-monothiofosfaat [Dutch]; O,O-Dimethyl-S-(3-oxo-3-thia-pentyl)-monothiophosphat [German]; O,O-Dimetil-S-(2-etil-solfinil-etil)-monotiofosfato [Italian]; Oxydemeton-methyl; Oxydemeton-metile [Italian]; Oxydemetonmethyl; Phosphorothioic acid, O,O-dimethyl S-(2-(ethylsulfinyl)ethyl) ester; Phosphorothioic acid, S-(2-(ethylsulfinyl)ethyl) O,O-dimethyl ester; R 2170; S-(2-(Ethylsulfinyl)ethyl) O,O-dimethl phosphorothioate; S-(2-(Ethylsulfinyl)ethyl) O,O-dimethyl phosphorothioate; S-2-Ethylsulphinylethyl O,O-dimethyl phosphorothioate; Thiophosphate de O,O-dimethyle et de S-2-ethylsulfinylethyle [French]; S-(2-(Ethylsulfinyl)ethyl) O,O-dimethyl ester phosphorothioic acid; [ChemIDplus] UN2784

Category

Organophosphate Insecticides

Description

Colorless or yellow liquid; [HSDB] Clear amber liquid; [CAMEO]

Sources/Uses

Used as systemic insecticide and acaricide for cotton, vegetables, fruits, and field crops; [HSDB]

Comments

A cholinesterase inhibitor; Can be absorbed through skin; [CAMEO] A woman who was five months pregnant attempted suicide by ingestion and was hospitalized with symptoms including miosis, respiratory distress, muscular fasciculations, and coma (12 hours after admittance); Blood cholinesterase was reduced by 90%; The remainder of her pregnancy was without incident, and the babys neurological exams at birth and 8 days later were normal; [HSDB] Occupational exposure less likely to be symptomatic or require hospitalization than exposure to other cholinesterase inhibitors; [Reference #1]

Restricted

Banned in the EU for use as pesticide for plant protection; [eChemPortal: ESIS] Restricted use pesticide (RUP); [Reference #1]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Vapor Pressure

2.85E-5 mm Hg

Lethal Concentration

LC50 (rat) = 427 mg/m3/1h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, flammable, toxic."

Reference Link

INCHEM JMPR: Oxydemeton-methyl - 2002

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: