Agent Name

p-Chloroacetanilide

CAS Number

539-03-7

Formula

C8-H8-Cl-N-O

Major Category

Nitrogen Compounds

Synonyms

4-Chloroacetanilide; Acetamide, N-(4-chlorophenyl)-; Acetanilide, 4'-chloro-; Acetic acid, amide, N(4-chlorophenyl)-; Acetic-4-chloroanilide; N-(4-Chlorophenyl)acetamide; N-(p-Chlorophenyl)acetamide; N-Acetyl-p-chloroaniline; [ChemIDplus]

Category

Other Aromatics (Nitrogen)

Description

Solid; [HSDB] White or light brown powder; [Alfa Aesar MSDS]

Sources/Uses

A soil bacteria metabolite of 4-chloroaniline and contaminant of phenacetin; Used as research chemical; Not commercially produced in the US; [HSDB]

Comments

Causes Heinz body formation, hemolysis, and spleen enlargement in rats; Exhibits nephrotoxic and hepatotoxic potential in intraperitoneal studies of rats; [HSDB] Causes decreased body temperature in intraperitoneal lethal-dose studies of rats; [RTECS] A skin and strong eye irritant; [Alfa Aesar MSDS] See "Acetanilide."

Exposure Assessment
Vapor Pressure

9.63E-5 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Other Information

No other related information on this agent was found.