Agent Name

Padimate O

CAS Number

21245-02-3

Formula

C17-H27-N-O2

Major Category

Other Uses

Synonyms

Octyl dimethyl PABA; Octyl dimethyl p-aminobenzoate; 2-Ethylhexyl p-(dimethylamino)benzoate; 2-Ethylhexyl p-dimethylaminobenzoate; Arlatone UVB; Benzoic acid, 4-(dimethylamino)-, 2-ethylhexyl ester; Escalol 507; Eusolex 6007; 4-(Dimethylamino)benzoic acid, 2-ethylhexyl ester; [ChemIDplus]

Category

Sunscreens

Description

Pale yellow liquid; [MSDSonline]

Sources/Uses

Used as ultraviolet screen; [Merck Index]

Comments

It is tested at a concentration of 5% in petrolatum and is a rare sensitizer; Patients may be allergic or photallergic with cross-reaction with other PABA sunscreens; [Marks, p. 218] No photo-toxicity; No sensitization except for slight reactions; [European Commission] High dose feeding studies with rats produced toxicity to testes, epididymis, spleen, and liver; Following four weeks of recovery, effects seemed reversible except for marked epididymal hypospermia in all animals dosed at 1000 mg/kg/day; [HSDB] Not irritating, sensitizing, nor photosensitizing, based on animal and limited human studies; [MSDSonline]

Adverse Effects
Skin Sensitizer

Yes

Dermatotoxin

Contact Dermatitis, Photoallergic

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: