Agent Name

Palmotoxin Bo

CAS Number

39450-10-7

Major Category

Biological Agents

Synonyms

Palmotoxin B0; Palmotoxin B(0); [ChemIDplus]

Category

Mycotoxins

Sources/Uses

A highly toxic fluorescent metabolite of Aspergillus flavus; [ChemIDplus] A mycotoxin from Aspergillus flavus and Elaeis guineesis; [HSDB]

Comments

Evidence of growth retardation, teratogenesis, and hepatotoxicity in animal studies; Much less potent as a mutagen than aflatoxin B1 or M1; Aflatoxin B1, Palmotoxin Bo, and Palmotoxin Go were all toxic to developing chick embryos, causing decreased body and organ weights, but Palmotoxin Bo was less potent than the other two substances; In rats treated for 15 days with up to 6.4 mg/kg/day, Palmotoxin Bo caused weight loss and liver injury and Palmotoxin Go did not. [HSDB]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

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Health Studies

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Chemical Information

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Other Information

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