Agent Name

Santonox

Alternative Name

4,4`-Thiobis-(6-tert-butyl-m-cresol)

CAS Number

96-69-5

Formula

C22-H30-O2-S

Major Category

Plastics & Rubber

Synonyms

4,4`-Thiobis-(6-tert-butyl-m-cresol); 1,1'-Thiobis(2-methyl-4-hydroxy-5-tert-butylbenzene); 4,4'-Thiobis(2-(1,1-dimethylethyl)-5-methylphenol); 4,4'-Thiobis(2-tert-butyl-5-methylphenol); 4,4'-Thiobis(3-methyl-6-tert-butylphenol); 4,4'-Thiobis(6-tert-butyl-3-methylphenol); 4,4'-Thiobis(6-tert-butyl-m-cresol); Antage Crystal; Antioxidant AO; Antioxidant TMB 6; Bis(3-tert-butyl-4-hydroxy-6-methylphenyl) sulfide; Bis(4-hydroxy-5-tert-butyl-2-methylphenyl) sulfide; Disperse MB-61; Nocrac 300; Nonflex BPS; Santonox; Santonox BM; Santonox R; Santowhite crystals; Santox; Sumilizer WX; Sumilizer WX-R; Thioalkofen BM 4; Thioalkofen BMCH; Thioalkofen MBCH; Thioalkophene BM-4; Yoshinox S; Yoshinox SR; [ChemIDplus]

Category

Curing Agents (Aromatic)

Description

Light-gray to tan powder with a slightly aromatic odor; [NIOSH]

Sources/Uses

Used as an antioxidant in the manufacturing of synthetic rubber and plastics; [HSDB]

Comments

Liver toxicity observed in 2-year feeding studies of rodents; Two patients had positive patch tests after developing contact dermatitis from latex gloves containing Santonox, but this was not confirmed in three other studies that found no evidence of skin sensitization; TLV Basis is respiratory tract irritation; [ACGIH] A skin, eye, and respiratory tract irritant; [CAMEO]

Exposure Assessment
Skin Designation (ACGIH)

No

TLV (ACGIH)

1 mg/m3, Inhalable particulate matter

PEL (OSHA)

15 mg/m3(total dust), 5 mg/m3(respirable fraction)

Explanatory Notes

Flash point = 420 deg F; VP from Cameo = 0.0000006 @ 158 deg F;

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Processes

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