Agent Name

Paraoxon

CAS Number

311-45-5

Formula

C10-H14-N-O6-P

Major Category

Pesticides

Synonyms

Chinorta; Chinorto; Diaethyl-p-nitrophenylphosphorsaeureester [German]; Diethyl 4-nitrophenyl phosphate; Diethyl p-nitrophenyl phosphate; Diethyl paraoxon; Diethyl-p-nitrofenyl ester kyseliny fosforecne [Czech]; Diethylparaoxon; E 600; E 600 (pesticide); ENT 16,087; Ester 25; Ethyl p-nitrophenyl ethylphosphate; Ethyl paraoxan; Ethyl paraoxon; Eticol; Fosfakol; HC 2072; Mintaco; Mintacol; Mintisal; Miotisal; Miotisal A; O,O'Diaethyl-p-nitrophenylphosphat [German]; O,O-Diethyl O-p-nitrophenyl phosphate; O,O-Diethyl phosphoric acid O-p-nitrophenyl ester; O,O-Dietyl-O-p-nitrofenylfosfat [Czech]; Oxyparathion; Paraoxone; Paroxan; Pestox 101; Phenol, p-nitro-, ester with diethyl phosphate; Phosphachole; Phosphacol; Phosphakol; Phosphoric acid diethyl 4-nitrophenyl ester; Phosphoric acid, diethyl p-nitrophenyl ester; Soluglacit; Soluglaucit; Ts 219; p-Nitrophenyl diethyl phosphate; p-Nitrophenyl diethylphosphate; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Reddish-yellow odorless liquid; [Hawley] Mild fruity odor; [CAMEO]

Sources/Uses

Used as insecticide; [Merck Index] A metabolite of the pesticide parathion (formed by microbial degradation, chemical oxidation, irradiation, and conversion in air promoted by sunlight); Formerly used to treat glaucoma; [HSDB]

Comments

The oxygen analog of parathion; A cholinesterase inhibitor; [Hawley] May have detrimental effects on immune and hematopoietic systems; Mutagenic effects to Salmonella and Schizosaccharomyces pombe and sister chromatid exchanges in hamster ovary cells; No evidence of delayed neurotoxicity in study with hens; [HSDB] See "Parathion."

Restricted

Not registered for use as pesticide in the US; [HSDB]

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Vapor Pressure

1.1E-6 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: