Agent Name

Pentachlorodibenzo-p-dioxin

CAS Number

36088-22-9

Formula

C12-H3-Cl5-O2

Major Category

Other Classes

Synonyms

Dibenzo(b,e)(1,4)dioxin, pentachloro-; [ChemIDplus]

Category

Halogenated Polyaromatics

Sources/Uses

Released to the environment in emissions from wood combustion, waste oil furnaces, fires of materials containing PVC, fires of electrical equipment containing polychlorinated biphenyls (PCBs), and cigarette smoke; Found in 2,4,5-T and other pesticides; Released in effluents from the pulp and paper industries, and in municipal sewage; Can be produced by thermal and chemical degradation of chlorophenols; [HSDB]

Comments

IARC classification is for polychlorinated dibenzo-para-dioxins other than 2,3,7,8-Tetrachlorodibenzo-p-dioxin; Polychlorodibenzodioxins have caused chloracne in humans; Occupational exposure may occur in metal reclamation, during use or manufacture of chlorophenol, or during herbicide manufacture; Oral LD50 (rat) = 0.206 mg/kg for the 1,2,3,7,8- isomer; [HSDB] See "2,3,7,8-Tetrachlorodibenzo-p-dioxin."

Exposure Assessment
Vapor Pressure

5.6E-10 mm Hg

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Chloracne

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

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