Agent Name

Perfluorooctylsulfonyl fluoride

Alternative Name

POSF

CAS Number

307-35-7

Formula

C8-F18-O2-S

Major Category

Other Classes

Synonyms

POSF; 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluoro-1-octanesulfonyl fluoride; 1-Octanesulfonyl fluoride, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-; N-Perfluorooctanesulfonyl fluoride; Perfluorooctanesulfonyl fluoride; Heptadecafluorooctanesulphonyl fluoride; [ChemIDplus] POSF; [EPA]

Category

Other Organic Compounds

Description

Clear liquid; [MSDSonline]

Sources/Uses

Used as a precursor for various perfluorinated amides, alcohols, acrylates, and other fluorochemical polymers; [EPA]

Comments

Emergency treatment: "Fluoride"; [HSDB] Repeated high-dose studies have shown the liver to be the primary target organ; Effects observed in reproductive studies include increase in neonatal mortality; Multi-generational studies showed no effects to post-natal neurological development or to fertility in offspring; No evidence of mutagenicity; Perfluorooctanesulfonyl fluoride (POSF) based fluorochemicals can be absorbed into the body and metabolized into perfluorooctanesulfonate (PFOS); Monitoring of PFOS has been used to measure employee exposure to POSF based chemicals in manufacturing; [EPA] See "Perfluorooctane sulfonic acid."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Other Information

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