Agent Name

1,2,4-Trichlorobenzene

CAS Number

120-82-1

Formula

C6-H3-Cl3

Major Category

Solvents

Synonyms

1,2,4-Trichlorobenzene; 1,2,4-Trichlorobenzol; 1,3,4-Trichlorobenzene; Hostetex L-pec; Trojchlorobenzen [Polish]; unsym-Trichlorobenzene; [ChemIDplus] UN2321

Category

Chlorinated Aromatics

Description

Colorless liquid or crystalline solid (below 63 degrees F) with an aromatic odor; [NIOSH]

Sources/Uses

Used as a dielectric and heat transfer fluid and as an intermediate for other organic chemicals; [ACGIH] Used as a degreaser, wood preservative, and dye solvent; [HSDB]

Comments

Animal studies show 1,2,4-trichlorobenzene to be toxic to the liver, kidneys, and brain (central nervous system depressant). [ACGIH] A skin, eye, and respiratory tract irritant; May cause liver injury; [ICSC]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

Ceiling (ACGIH)

5 ppm

Vapor Pressure

0.46 mm Hg

Odor Threshold Low

2.96 ppm

Explanatory Notes

Odor threshold from AIHA; Flash point = 105 deg C;

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: