Agent Name

Phenoxarsine oxide

CAS Number

58-36-6

Formula

C24-H16-As2-O3

Major Category

Metals

Synonyms

10,10'-Bis(phenoxyarsinyl) oxide; 10,10'-Oxidiphenoxarsine; 10,10'-Oxybis-10H-phenoxarsine; 10,10'-Oxybisphenoxarsine; 10,10'-Oxybisphenoxy-arsine; 10,10'-Oxydiphenoxarsine; 10-10' Oxybisphenoxyarsine; 10H-Phenoxarsine, 10,10'-oxybis-; Bis(10-phenoxarsinyl)oxide; Bis(10-phenoxarsyl) oxide; Bis(10-phenoxyarsinyl) oxide; Bis(phenoxarsin-10-yl) ether; DID 47; Durotex; OBPA; Phenoxarsine, 10,10'-oxydi-; Phenoxyarsine, 10,10'-oxybis-; SA 546; Vinadine; Vinyzene; Vinyzene (pesticide); Vinyzene BP 5; Vinyzene BP 5-2; Vinyzene SB 1; 10H-Phenoxarsine, 10,10'-oxybis-; Diphenoxarsin-10-yl oxide; [ChemIDplus]

Category

Arsenic Compounds, Organic

Description

Colorless solid; [Merck Index] White crystalline solid; [MSDSonline]

Sources/Uses

Used to protect plastics and textiles from fungi and bacteria; [HSDB] Used as a bacteriocide/germicide and fungicide in shower curtains, floor and wall coverings, coated fabrics, marine upholstery, vinyl moldings, awnings, weather stripping, and swimming pool liners; Also used as a preservative in adhesives, coatings, carpets, and other products (paper, plastic, and textile); [EPA REDs]

Comments

Severely irritating to skin; Toxic by ingestion and inhalation; Oral LD50 (rat) = 40 mg/kg; [Sax] Retards growth and causes liver effects in high-dose feeding studies; No developmental, reproductive, or mutagenic effects; Arsenic accumulates in liver and kidneys of exposed animals with clearing 2 weeks after last exposure; $The potential for occupational exposure to OBPA is minimal provided that OBPA is used in a closed system and that appropriate Personal Protective Equipment (PPE) is worn.$ [EPA REDs] An irritant that can cause skin burns; May be lethal if ingested or inhaled; May cause liver and kidney damage; [MSDSonline] $Almost nothing is known regarding health effects of organic arsenic compounds in humans. Studies in animals show that some simple organic arsenic compounds are less toxic than inorganic forms. Ingestion of methyl and dimethyl compounds can cause diarrhea and damage to the kidneys.$ [ATSDR ToxProfiles]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
PEL (OSHA)

0.5 mg/m3, as As

Lethal Concentration

LCLo (guinea pigs) = 141 mg/m3/2h

Adverse Effects
Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: