Agent Name

Trichloronaphthalene

CAS Number

1321-65-9

Formula

C10-H5-Cl3

Major Category

Other Classes

Synonyms

Halowax; Naphthalene, trichloro-; Nibren; Nibren wax; Seekay wax; [ChemIDplus]

Category

Halowaxes

Description

Colorless to pale-yellow solid with an aromatic odor; [NIOSH]

Sources/Uses

Used in lubricants and in the manufacture of electrical wire insulation; [ACGIH]

Comments

Chlorinated naphthalenes may be absorbed through the skin. They cause liver injury and hyperkeratosis in experimental animals. Penta- and hexachloronaphthalene may cause in exposed workers acne-like lesions that itch severely. Tri-, tetra-, and octachloronaphthalene are non-acnegenic under the conditions of industrial use. Nine occupational fatalities from chlorinated naphthalene poisoning have been reported. Most cases of intoxication among cable workers, assemblers, and laborers involve either penta- or hexachloronaphthalene. A nonfatal case of toxic hepatitis was reported in an 18 year old female who was soldering electrical condensers. [ACGIH] Acne-form dermatitis is listed as an adverse effect for all of the halowaxes except trichloronaphthalene in the Pocket Guide. [NIOSH] A mild skin and eye irritant; May cause liver injury; [ICSC]

Reference Link

CHLORINATED NAPHTHALENES (CICAD 34, 2001)

Exposure Assessment
Skin Designation (ACGIH)

Yes

Bioaccumulates

Yes

TLV (ACGIH)

5 mg/m3

PEL (OSHA)

5 mg/m3

Excerpts from Documentation for IDLHs

Animal data: Rats and mice exposed to a single 2hour exposure to 200 mg/m3 had no adverse effects [Shakahnovskava 1953]. . . . Basis for revised IDLH: Due to a lack of relevant acute toxicity data, the IDLH for trichloronaphthalene remains "Unknown."

Vapor Pressure

0.000314 mm Hg

Explanatory Notes

Flash point = 200 deg C;

Adverse Effects
Hepatotoxin

Hepatotoxin, Primary

Dermatotoxin

Chloracne

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Diseases

Occupational diseases associated with exposure to this agent: