Agent Name

Trifluorobromomethane

Alternative Name

Bromotrifluoromethane

CAS Number

75-63-8

Formula

C-Br-F3

Major Category

Solvents

Synonyms

Bromofluoroform; Bromotrifluoromethane; Carbon monobromide trifluoride; Daiflon 13B1; F 13B1; F-13B1; FC 13B1; FE 1301; Flugex 13B1; Fluorocarbon 1301; Freon 13B1; Halocarbon 13B1; Halon 1301; Khladon 13B1; Monobromotrifluoromethane; R 13B1; Refrigerant 13B1; Trifluorobromomethane; Trifluoromethyl bromide; Trifluoromonobromomethane; [ChemIDplus] UN1009

Category

Chlorofluorocarbons

Description

Colorless, odorless gas. [Note: Shipped as a liquefied compressed gas.]; [NIOSH]

Sources/Uses

Used as a fire extinguisher and chemical intermediate; [ACGIH]

Comments

Slightly increased reaction times were recorded in volunteers exposed to 4% trifluorobromomethane for 3 minutes. [ACGIH] Possible frostbite from contact with liquid; [NIOSH] An eye irritant; Evaporating liquid can cause frostbite; Inhalation of high concentrations can cause CNS depression; [ICSC] See "CHLOROFLUOROCARBONS."

Restricted

See CHLOROFLUOROCARBONS

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

1000 ppm

PEL (OSHA)

1000 ppm

MAK

1000 ppm

IDLH (NIOSH)

40000 ppm

Excerpts from Documentation for IDLHs

Human data: Volunteers exposed to 70,000 ppm for 3 minutes experienced lightheadedness and disturbances in balance and ability to respond to visual stimulus [Reinhardt and Reinke 1972]; 3 hours to 70,000 ppm caused decrements in mental performance tests [Harrison et al. 1982]. Exposure to 50,000 ppm for 20 to 25 minutes caused drowsiness, lightheadedness, and a slight effect on judgment [Hine et al. 1968]. Three volunteers experienced mild nose and throat discomfort after 28 minutes of exposure to 71,000 ppm [Stewart et al. 1978]. Others reported that a 30minute exposure at 43,000 to 45,000 ppm caused dizziness, lightheadedness, euphoria, and disturbances in equilibrium and coordination [Stewart et al. 1978].

Lethal Concentration

LC50 (rat) = 84,000 ppm/15 min

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Simple Asphyxiant

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: