Agent Name

Phosmet

CAS Number

732-11-6

Formula

C11-H12-N-O4-P-S2

Major Category

Pesticides

Synonyms

(O,O-Dimethyl-phthalimidiomethyl-dithiophosphate); APPA; Decemthion; Decemthion P-6; Decemtion P-6; ENT 25,705; Fosmet; Ftalophos; Imidan; Imidan 5 Dust; Imidan WP; Imidathion; Kemolate; N-(Dimethoxyphosphinothioylthiomethyl)phthalimide; N-(Mercaptomethyl)phthalimide S-(O,O-dimethyl phosphorodithioate); O,O-Dimethyl S-(N-phthalimidomethyl)dithiophosphate; O,O-Dimethyl S-(phthalimididomethyl)phosphorodithioate; O,O-Dimethyl S-(phthalimidomethyl) dithiophosphate; O,O-Dimethyl S-(phthalimidomethyl)phosphorodithioate; O,O-Dimethyl S-phthalimidomethyl phosphorodithioate; O,O-Dimethyl phosphorodithioate S-ester with N-(mercaptomethyl)phthalimide; PMP; PMP (pesticide); Percolate; Phosphorodithioic acid O,O-dimethyl ester S-ester with N-(mercaptomethyl) phthalimide; Phosphorodithioic acid, O,O-dimethyl ester, S-ester with N-(mercaptomethyl)phthalimide; Phosphorodithioic acid, S-((1,3-dihydro-1,3-dioxo-isoindol-2-yl)methyl) O,O-dimethyl ester; Phtalofos; Phthalimide, N-(mercaptomethyl)-, S-ester with O,O-dimethyl phosphorodithioate; Phthalimidomethyl O,O-dimethyl phosphorodithioate; Phthalophos; Prolate; Prolate 5 Dust; Prolate 8-OS; Prolate E; R 1504; R-1504; S-((1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl) O,O-dimethyl phosphorodithioate; S-((1,3-Dioxo-2H-isoindol-2-yl)methyl) O,O-dimethyl phosphorodithioate; Safidon; Simidan; Smidan; Stauffer R 1504; [ChemIDplus] UN2783

Category

Organophosphate Insecticides

Description

Colorless to off-white solid; [ICSC] Technical product is off-white or pink solid with an offensive odor; [HSDB] Colorless solid; [MSDSonline]

Sources/Uses

Used as non-systemic acaricide and insecticide for fruits, nuts, berries, cotton, ornamentals, other crops, and livestock; [HSDB]

Comments

A cholinesterase inhibitor that may cause CNS effects resulting in convulsions and respiratory depression; Can be absorbed through skin; [ICSC] Highly toxic cholinesterase inhibitor; [CAMEO] A man who attempted suicide by ingestion was brought by friend to emergency room with symptoms including oral and bronchial secretions and respiratory distress requiring intubation; Within an hour health care personal began developing symptoms of poisoning; A nursing assistant who had contact with the patients skin and bodily fluids required intubation and was hospitalized for 9 days; Two nurses who were exposed only by inhalation in close proximity to the patient developed symptoms including confusion, nausea, abdominal cramps, and dyspnea; Many poisoning cases have been reported from the use of animal dips and shampoos by pet owners, groomers, and veterinary assistants; [HSDB] Not likely to be teratogenic, based on animal studies; [REPROTOX]

Restricted

Cancelled--no longer registered for residential pesticide uses (domestic pets and home gardens) in the US; [HSDB]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Vapor Pressure

4.9E-7 mm Hg

Lethal Concentration

LC50 (rat) > 152 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, solid, toxic."

Reference Link

INCHEM JMPR: Phosmet (addendum) - 2003

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: