Agent Name

Phosphonothioic acid, methyl-, O-(4-nitrophenyl) O-phenyl ester

CAS Number

2665-30-7

Formula

C13-H12-N-O4-P-S

Major Category

Pesticides

Synonyms

CP 40294; Colep; ENT 25,787; Monsanto CP-40294; O-(4-Nitrophenyl) O-phenylmethylphosphonothioate; O-(p-Nitrophenyl) O-phenyl methylphosphonothioate; O-Fenyl-O-p-nitrofenylester kyseliny methylthiofosfonove [Czech]; Phosphonothioic acid, methyl-, O-(p-nitrophenyl) O-phenyl ester; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Liquid; [CAMEO]

Sources/Uses

Used as broad spectrum insecticide; Has not been marketed; [HSDB]

Comments

A cholinesterase inhibitor; [CAMEO] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: