Agent Name

Piperonal

CAS Number

120-57-0

Formula

C8-H6-O3

Major Category

Biological Agents

Synonyms

1,3-Benzodioxole-5-carboxaldehyde; 3,4-Bis(methylenedioxy)benzaldehyde; 3,4-Dihydroxybenzaldehyde methylene ketal; 3,4-Dimethylenedioxybenzaldehyde; 3,4-Methylene-dihydroxybenzaldehyde; 3,4-Methylenedioxybenzaldehyde; 5-Formyl-1,3-benzodioxole; Benzaldehyde, 3,4-(methylenedioxy)-; Dioxymethylene protocatechuic aldehyde; Dioxymethylene-protocatechuic aldehyde; Geliotropin; Heliotropin; Heliotropin (natural); Heliotropine; Piperonaldehyde; Piperonyl aldehyde; Piperonylaldehyde; Protocatechuic aldehyde methylene ether; [ChemIDplus]

Category

Plant Oils and Extracts

Description

Colorless lustrous solid; mp = 37 deg C; [Merck Index] White shining solid with a floral odor; Darkens to red-brown on light exposure; mp = 35.5-37 deg C; [Hawley] Colorless solid; mp = 36 deg C; [MSDSonline]

Sources/Uses

Found in various essential oils; Used in fragrances, flavoring agents, and suntan preparations; Also used as a mosquito repellent, laboratory reagent, organic intermediate, and synergist for pyrethrum and rotenone; [HSDB]

Comments

A skin irritant; May cause CNS depression; Emergency treatment: Irritants; [HSDB] An irritant; May cause CNS depression; [CAMEO] Safe when used as a flavoring agent in food; [JECFA] Caused hepatocellular necrosis in rats receiving intermittent doses for 6 weeks at >2100 mg/kg; [RTECS]

Exposure Assessment
Vapor Pressure

0.01 mm Hg

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

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Health Studies

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Chemical Information

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