Agent Name

Pirimiphos-ethyl

CAS Number

23505-41-1

Formula

C13-H24-N3-O3-P-S

Major Category

Pesticides

Synonyms

2-Diethylamino-6-methyl-4-pyrimidinyl diethyl phosphorothioate; 2-Diethylamino-6-methylpyrimidin-4-yl diethyl phosphorothionate; 2-Diethylamino-6-methylpyrimidin-4-yl diethylphosphorothionate; Ethyl pirimiphos; Fernex; O,O-Diethyl O-(2-(diethylamino)-6-methyl-4-pyrimidinyl) phosphorothioate; O,O-Diethyl O-(2-diethylamino-6-methyl-4-pyrimidinyl)phosphorothioate; O-(2-(Diethylamino)-6-methyl-4-pyrimidinyl) O,O-diethyl phosphorothioate; O-(2-(Diethylamino)-6-methyl-4-pyrimidinyl)O,O-diethyl phosphorothioate; O-(2-(Diethylamino)-6-methyl-4-pyrimidinyl)phosphorothioic acid O,O-diethyl ester; PP211; Phosphorothioic acid, O-(2-(diethylamino)-6-methyl-4-pyrimidinyl) O,O-diethyl ester; Pirimifosethyl; Pirimiphos ethyl; Pirimifos-ethyl; Primicid; Primotec; Pyrimiphos-ethyl (ISO-French); R 42211; Solgard; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Straw colored liquid; [Merck Index] Technical product is clear red-brown liquid; mp 15-18 deg C; [HSDB] Yellow liquid; mp = 10-15 deg C; [MSDSonline]

Sources/Uses

Used as broad spectrum contact and fumigant insecticide and veterinary ectoparasiticide; [Merck Index] Used for fruits, ornamentals, turf, vegetables, and other crops; Also used in combination with fungicides for seed treatment; [HSDB]

Comments

A cholinesterase inhibitor; Can be absorbed through skin; [CAMEO] No effects observed besides inhibition of cholinesterase in 90 day animal feeding studies; No skin irritation or sensitization observed in rabbits; [HSDB] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Restricted

Cancelled--no longer registered as a pesticide for use in the US; [HSDB]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

0.00029 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Adverse Effects
Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: