Agent Name

1,3-Benzenedimethanamine

Alternative Name

m-Xylene alpha,alpha'-diamine

CAS Number

1477-55-0

Formula

C8-H12-N2

Major Category

Nitrogen Compounds

Synonyms

m-Xylene alpha,alpha'-diamine; 1,3-Benzenedimethanamine; 1,3-Bis(aminomethyl)benzene; 1,3-Bis-aminomethylbenzen [Czech]; 1,3-Xylylenediamine; Methylamine, m-phenylenebis-; alpha,alpha'-Diamino-m-xylene; m-Phenylenebis(methylamine); m-Xylene-alpha,alpha'-diamine; m-Xylylendiamin [Czech]; m-Xylylenediamine; [ChemIDplus]

Category

Amines, Aromatic

Description

Colorless liquid; [NIOSH]

Sources/Uses

Curing agent for epoxy resins; [ACGIH]

Comments

In animals the undiluted liquid is corrosive, and the 50% emulsion causes severe skin irritation. Workers in plastics production have developed skin sensitization.[ACGIH] Rats exposed for 1 hour to an aerosol ranging from 1.74 to 6.04 mg/liter have lacrimation and labored breathing. Some animals die within the following 2-14 days. Necropsy findings include changes mainly to lungs, but also to the liver and kidneys. [ACGIH] Can cause severe burns; [CHEMINFO]

Reference Link

[Allergic contact eczema caused by m-xylylene-diamine in the polyurethane silk production]

Exposure Assessment
Skin Designation (ACGIH)

Yes

Ceiling (ACGIH)

0.1 mg/m3

Vapor Pressure

0.03 mm Hg

Lethal Concentration

LC50 (rat) = 700 ppm/1h

Explanatory Notes

Flash point =117 deg C; See "2018 Notice of Intended Changes." [TLVs and BEIs]

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: