Disease/Syndrome

Cholangiocarcinoma

Category

Cancer, Occupational

Acute/Chronic

Chronic

Synonyms

Cancer of the biliary tract

Comments

"There is sufficient evidence in humans for the carcinogenicity of 1,2-dichloropropane. 1,2-Dichloropropane causes cancer of the biliary tract (confirmed as cholangiocarcinoma). . . . However, a minority of the Working Group concluded that the association between 1,2-dichloropropane and cancer of the biliary tract was credible, but the role of exposure to other agents, principally dichloromethane, could not be separated with complete confidence, and noted that most of the evidence came from studies in a single plant." [IARC 2016]

Latency/Incubation

Years

Diagnostic

Histopathological examination;

ICD-9 Code

155.9

Reference Link

Cholangiocarcinoma among offset colour proof-printing workers exposed to 1,2-dichloropropane and/or dichloromethane

Related Information in Haz-Map
Agents

Hazardous agents that cause the occupational disease: