Agent Name

Pirimiphos-methyl

CAS Number

29232-93-7

Formula

C11-H20-N3-O3-P-S

Major Category

Pesticides

Synonyms

2-Diethylamino-6-methylpyrimidin-4-yl dimethyl phosphorothionate; Actelic; Actellic; Actellifog; Aktelik; Aktellik; BLEX; Fosforan pirimidyny [Polish]; Methylpirimiphos; O,O-Dimethyl O-(2-(diethylamino)-6-methyl-4-pyrimidinyl) phosphorothioate; O-(2-Diethylamino-6-methylpyrimidin-4-yl) O,O-dimethyl phosphorothioate; OMS 1424; PP511; Pirimifosmethyl; Pirimiphos methyl; Primiphos-methyl; Plant protection PP511; Pyridimine phosphate; Pyrimiphos methyl; Pyrimiphos-methyl [ISO-French]; R 33986; Silosan; Sybol 2; O-(2-(Diethylamino)-6-methyl-4-pyrimidinyl) O,O-dimethylphosphorothioate; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Straw colored liquid; mp = 15-18 deg C (technical grade); [HSDB]

Sources/Uses

Used as insecticide and veterinary ectoparasiticide; [Merck Index] Used to control insects and mites in vegetables, warehouses, stored grain, animal housings, and domestic and industrial areas; [HSDB] Registered in the US as general use classification insecticide for sorghum and corn (seed and stored), cattle ear tags, and fogging iris bulbs; [Reference #1]

Comments

Effects observed in two week study with rats include weight loss, decreased hemoglobin, and reticulocytosis; Minor reversible bile duct proliferation and liver damage observed in 90 day feeding study with dogs; Caused minor skin and eye irritation in rabbits; No evidence of skin sensitization in guinea pigs; [HSDB]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Vapor Pressure

1.5E-5 mm Hg

Lethal Concentration

LC (rat) > 5040 mg/m3/4h

Reference Link

INCHEM JMPR: Pirimiphos-methyl

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Other Poison

Organophosphate

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: