Agent Name

Proflavine

CAS Number

92-62-6

Formula

C13-H11-N3

Major Category

Other Uses

Synonyms

2,8-Diaminoacridine (European); 2,8-Diaminoacridinium; 3,6-Diaminoacridine; 3,6-Diaminoacridinium; 3,7-Diamino-5-azaanthracene; Isoflav base; Proflavin; Proflavina [INN-Spanish]; Proflavinum [INN-Latin]; 3,6-Acridinediamine; Acridine, 3,6-diamino-; [ChemIDplus]

Category

Biocides/Disinfectants

Description

Yellow solid; [Merck Index]

Sources/Uses

Used as a topical antiseptic; [Merck Index] Proflavine impregnated wool is used by some UK plastic surgeons; [HSDB] Used in the treatment of psoriasis and herpesvirus infections; [NTP]

Comments

Proflavine and its salts are used as topical antiseptics; No epidemiological studies available and animal data inadequate for evaluation; [IARC] Allergic contact dermatitis has been reported; [HSDB] Intraperitoneal LD50 (mouse) = 50 mg/kg; [Sax] An irritant; [MSDSonline]

Exposure Assessment
Vapor Pressure

8.94E-8 mm Hg

Adverse Effects
IARC Carcinogen

Not Classifiable

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Health Studies

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Toxicity Information

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Chemical Information

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Processes

Industrial Processes with risk of exposure: