Agent Name

Propylparaben

CAS Number

94-13-3

Formula

C10-H12-O3

Major Category

Other Uses

Synonyms

4-Hydroxybenzoic acid propyl ester; Aseptoform P; Benzoic acid, 4-hydroxy-, propyl ester; Benzoic acid, p-hydroxy-, propyl ester; Betacide P; Betacine P; Bonomold OP; Chemacide PK; Chemocide PK; Nipagin P; Nipasol; Nipasol M; Nipasol P; Nipazol; Paraben; Parasept; Paseptol; Preserval P; Propagin; Propyl 4-hydroxybenzoate; Propyl Parasept; Propyl aseptoform; Propyl butex; Propyl chemosept; Propyl p-hydroxybenzoate; Propyl paraben; Propyl parahydroxybenzoate; Propylester kyseliny p-hydroxybenzoove [Czech]; Propylparasept; Protaben P; Pulvis conservans (VAN); Solbrol P; Tegosept P; n-Propyl p-hydroxybenzoate; p-Hydroxybenzoic acid propyl ester; p-Hydroxybenzoic propyl ester; p-Hydroxypropyl benzoate; p-Oxybenzoesaurepropylester [German]; [ChemIDplus]

Category

Preservatives

Description

Colorless or white solid; [Hawley] White powder; [MSDSonline]

Sources/Uses

Used as antimicrobial preservatives in pharmaceuticals, foods, cosmetics, and shampoos; [HSDB] The parabens (methyl, ethyl, propyl, and butyl) were the most widely used preservatives in cosmetics (0.1% to 0.8%) until their sensitizing potential was recognized; [Marks, p. 115]

Comments

Parabens are an uncommon cause of allergic contact dermatitis; [Marks, p. 115] A moderate eye irritant (saturated aqueous solution); Parabens may cause skin sensitization in a small percentage of the population; [HSDB] May cause eye and respiratory tract irritation; Prolonged skin contact may cause irritation and contact dermatitis; [CAMEO] An eye and mild skin irritant; May cause skin sensitization; [eChemPortal: ERMA] "Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin." [Kanerva, p. 1822-3] May cause irritation; [MSDSonline]

Exposure Assessment
Vapor Pressure

0.000555 mm Hg

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: