Agent Name

Protopine hydrochloride

CAS Number

6164-47-2

Formula

C20-H19-N-O5.Cl-H

Major Category

Biological Agents

Synonyms

7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-, hydrochloride; Bis(1,3)benzodioxolo(4,5-c:5',6'-g)azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-, hydrochloride; PROTOPINE; Protopine HCl; [ChemIDplus]

Category

Plant Toxins

Description

Solid; [Merck Index]

Sources/Uses

Protopine: Found in opium and many herbs; [Merck Index]

Comments

Emergency treatment: Symptomatic drug ingestion; [HSDB] Intraperitoneal LD50 = 102 mg/kg; [RTECS] May cause irritation; Toxic if swallowed; Effects in high-dose animal studies include convulsions; Oral LD50 (mouse) = 160 mg/kg; [Aldrich MSDS]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Other Information

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