Agent Name

Quinoline

CAS Number

91-22-5

Formula

C9-H7-N

Major Category

Nitrogen Compounds

Synonyms

1-Azanaphthalene; 1-Benzazine; 2,3-Benzopyridine; B 500; B-500; Benzo(b)pyridine; Benzopyridine; Benzopyridine (VAN); Chinoleine; Chinolin [Czech]; Chinoline; Leucol; Leukol; Quinolin; [ChemIDplus] UN2656

Category

Quinolines

Description

Colorless hygroscopic liquid with characteristic odor; Turns brown after exposure to light; [ICSC] Clear liquid that darkens as ages; [Hawley] Light yellow liquid; [MSDSonline]

Sources/Uses

Used to make paints, dyes, and other chemicals; Also used as a preservative for anatomical specimens, solvent for resins and terpenes, fungistat, corrosion inhibitor, antimalarial drug, flavoring agent, and decarboxylation reagent; [HSDB] Extracted from coal-tar distillates; occurs in polluted air and cigarette smoke; [AIHA]

Comments

A skin and eye irritant; May have effects on the liver and retina; Possibly carcinogenic in humans; [ICSC] Causes lethargy, respiratory depression, and coma in high-dose animal experiments; No rats died when exposed to saturated vapor (about 78 ppm) for 8 hours, but all rats died within 6 hours after exposure to 4000 ppm; [HSDB] An irritant; May cause serious injury to eyes; Can be absorbed through skin; [MSDSonline]

Exposure Assessment
WEEL

0.001 ppm

Vapor Pressure

0.06 mm Hg

Odor Threshold Low

71 ppm

Explanatory Notes

Flash point = 105 deg C; [ICSC] Odor threshold from HSDB;

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Processes

Industrial Processes with risk of exposure: