Agent Name

Roquefortine

CAS Number

58735-64-1

Formula

C22-H23-N5-O2

Major Category

Biological Agents

Synonyms

Roquefortine C; 2H-Pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4(3H,5aH)-dione, 10b-(1,1-dimethyl-2-propenyl)-6,10b,11,11a-tetrahydro-3-(1H-imidazol-4-ylmethylene)-; 2H-Pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4-(3H,5aH)-dione, 6,10b,11,11a-tetrahydro-10b-(1,1-dimethyl-2-propenyl)-3-(1H-imidazol-4-ylmethylene)-; [ChemIDplus]

Category

Mycotoxins

Description

Solid; [MSDSonline]

Sources/Uses

A metabolite of Penicillium roqueforte (fungi used as a source of enzymes for blue-veined cheeses); [HSDB]

Comments

Intraperitoneal LD50 (mouse) = 15 mg/kg; [RTECS] May cause irritation; May be fatal by inhalation, skin absorption, and ingestion; May cause convulsions; Targets nerves; [MSDSonline]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Other Information

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