Agent Name

Ethyl acetate

CAS Number

141-78-6

Formula

C4-H8-O2

Major Category

Solvents

Synonyms

Acetate d'ethyle [French]; Acetato de etilo [Spanish]; Acetic acid, ethyl ester; Acetic ether; Acetidin; Acetoxyethane; Aethylacetat [German]; Essigester [German]; Ethyl acetate; Ethyl acetate (natural); Ethyl acetic ester; Ethyl ester; Ethyl ethanoate; Ethylacetaat [Dutch]; Ethylacetate; Ethyle (acetate d') [French]; Ethylester kyseliny octove [Czech]; Etile (acetato di) [Italian]; Octan etylu [Polish]; Vinegar naphtha; [ChemIDplus] UN1173

Category

Esters (<C12)

Description

A clear colorless liquid with a fruity odor; [CAMEO]

Sources/Uses

Used as a solvent for organic chemicals and surface coatings; [ACGIH]

Comments

Ethyl acetate is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] An eye and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC]

Reference Link

Volatile Substance Abuse

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

400 ppm

PEL (OSHA)

400 ppm

MAK

200 ppm

IDLH (NIOSH)

2000 ppm

Excerpts from Documentation for IDLHs

Workers regularly exposed to concentrations from 375 to 1,500 ppm for several months showed no unusual signs or symptoms [Patty 1963]. Concentrations in the range of 8,000 to 20,000 ppm have been considered dangerous for short exposures [Henderson and Haggard 1943].

Vapor Pressure

93.2 mm Hg

Odor Threshold Low

6.4 ppm

Odor Threshold High

50 ppm

RD50

614 ppm

Lethal Concentration

LC50 (mice) = 45,000 mg/m3/2H

Explanatory Notes

IDLH = 10% LEL; Detection odor threshold from AIHA (mean = 18 ppm); Flash point = 7.2 deg C;

Half Life

No reports found; [TDR, p. 625]

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure:

Activities

Activities with risk of exposure: